Compile Data Set for Download or QSAR
maximum 50k data
Found 124 of ic50 for ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA
having polymerids = 9680,49000388,49000775,50000831,50002849 and
complexids = 50000423,50000422,50000437,50000466,50005823,50014578,50000173,50000285,50000...
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023331((+)-pyrido[3,4-b]homotropane | (+/-)-pyrido[3,4-b]...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of [3H]-MCC binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023330(1-(9-Aza-bicyclo[4.2.1]non-2-en-2-yl)-ethanone | 1...)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of (-)-[3H]-nicotine binding to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023331((+)-pyrido[3,4-b]homotropane | (+/-)-pyrido[3,4-b]...)
Affinity DataIC50:  1nMAssay Description:inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataIC50:  1nMAssay Description:Inhibition of [3H]-MCC binding to rat brain membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023330(1-(9-Aza-bicyclo[4.2.1]non-2-en-2-yl)-ethanone | 1...)
Affinity DataIC50:  1nMAssay Description:inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataIC50:  4nMAssay Description:Inhibition of (-)-[3H]-nicotine binding to rat brain membranesMore data for this Ligand-Target Pair
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Rattus norvegicus)
Universit£

Curated by ChEMBL
LigandPNGBDBM50547500(CHEMBL4759352)
Affinity DataIC50:  6.60nMAssay Description:Inhibition of rat (alpha1)2betagammadelta expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced channel current respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023328(3-Pyrrolidin-2-yl-pyridine | CHEMBL1132 | Nornicot...)
Affinity DataIC50:  100nMAssay Description:inhibition of (-)-[3H]-nicotine binding to torpedo electroplax membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Homo sapiens)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567435(CHEMBL4872191)
Affinity DataIC50:  131nMAssay Description:Inhibition of human alpha1beta1deltaepsilon nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50049757(()-2-(6-Chloro-pyridin-3-yl)-7-aza-bicyclo[2.2.1]h...)
Affinity DataIC50:  160nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023327(3-Methyl-4,13-diaza-tricyclo[8.2.1.0*2,7*]trideca-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of [3H]-MCC binding to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023327(3-Methyl-4,13-diaza-tricyclo[8.2.1.0*2,7*]trideca-...)
Affinity DataIC50:  300nMAssay Description:Inhibition of (-)-[3H]-nicotine binding to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023328(3-Pyrrolidin-2-yl-pyridine | CHEMBL1132 | Nornicot...)
Affinity DataIC50:  300nMAssay Description:Inhibition of [3H]-MCC binding to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50094299(CHEMBL15998 | N-[(S)-1-(12-Amino-dodecylcarbamoyl)...)
Affinity DataIC50:  790nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50416397(CHEMBL1210515)
Affinity DataIC50:  794nMAssay Description:Antagonist activity at human alpha1 nAChR in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023329(13-Methyl-4,13-diaza-tricyclo[8.2.1.0*2,7*]trideca...)
Affinity DataIC50:  800nMAssay Description:Inhibition of (-)-[3H]-nicotine binding to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50416396(CHEMBL1210703)
Affinity DataIC50:  1.00E+3nMAssay Description:Antagonist activity at human alpha1 nAChR in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Torpedo californica)
Stauffer Chemical

Curated by ChEMBL
LigandPNGBDBM50023329(13-Methyl-4,13-diaza-tricyclo[8.2.1.0*2,7*]trideca...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of [3H]-MCC binding to rat brain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50604138(CHEMBL5184381)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of nicotinic acetylcholine receptor alpha 1 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50473035(CHEMBL342483)
Affinity DataIC50:  2.43E+3nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50381980(CHEMBL2022495)
Affinity DataIC50:  3.98E+3nMAssay Description:Antagonist activity at alpha1 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50413330(CHEMBL459689)
Affinity DataIC50:  3.98E+3nMAssay Description:Antagonist activity at human alpha-1-beta-1-gamma-delta nAChR expressed in human TE671 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352784(CHEMBL1823380)
Affinity DataIC50:  4.20E+3nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50473033(CHEMBL342258)
Affinity DataIC50:  4.47E+3nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50473023(CHEMBL342235)
Affinity DataIC50:  5.33E+3nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352785(CHEMBL1823381)
Affinity DataIC50:  5.50E+3nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50473029(CHEMBL140056)
Affinity DataIC50:  5.69E+3nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50322520((2S,3S)-2-Biphenyl-4-yl-3,5,5-trimethylmorpholin-2...)
Affinity DataIC50:  5.90E+3nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50472282(descyanothiacloprid)
Affinity DataIC50:  6.00E+3nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50413332(CHEMBL503427)
Affinity DataIC50:  6.31E+3nMAssay Description:Antagonist activity at human alpha-1-beta-1-gamma-delta nAChR expressed in human TE671 cells by calcium influx assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50382048(CHEMBL2022739)
Affinity DataIC50:  6.31E+3nMAssay Description:Antagonist activity at alpha1 nAChRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50322515((2S,3S)-2-(Naphthalen-1-yl)-3,5,5-trimethylmorphol...)
Affinity DataIC50:  6.60E+3nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50322518((+/-)2-(3,4-Dichlorophenyl)-3,5,5-trimethylmorphol...)
Affinity DataIC50:  7.20E+3nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50322516((+/-)2-(3,5-Dichlorophenyl)-3,5,5-trimethylmorphol...)
Affinity DataIC50:  7.20E+3nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50322532((2S,3S)-2-(3-Chlorophenyl)-3,5,5-trimethylmorpholi...)
Affinity DataIC50:  7.60E+3nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352786(CHEMBL1823382)
Affinity DataIC50:  7.80E+3nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50048392(2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one...)
Affinity DataIC50:  7.90E+3nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50078044(3-(6-Chloro-pyridin-3-ylmethyl)-3H-thiazol-(2E)-yl...)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of [3H]alpha-BGT binding to alpha1 nicotinic acetylcholine receptor in Homo sapiens (human) TE671 cells co-expressing gammaalpha1deltabeta...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50473036(CHEMBL141037)
Affinity DataIC50:  8.05E+3nMAssay Description:Antagonist activity at human muscle-type nAChR (embryonic muscle) expressed in TE671 cells; (end value).More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(Homo sapiens)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50567433(CHEMBL4869892)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human alpha1beta1deltaepsilon nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current respons...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352789(CHEMBL1823385)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352790(CHEMBL1823386)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50322512((2S,3S)-2-(3-Chlorophenyl)-5,5-dimethyl-3-propyl-m...)
Affinity DataIC50:  1.00E+4nMAssay Description:Antagonist activity at alpha-1-beta-1-gamma-delta nicotinic receptor in human TE671 cells assessed as inhibition varbamylcholine-induced radiolabeled...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50352791(CHEMBL1823387)
Affinity DataIC50: >1.00E+4nMAssay Description:Binding affinity to alpha1 nAchR expressed in human TE671 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(MOUSE)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50445331(CHEMBL3104245)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of mouse alpha1beta1deltaepsilon nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current after 2 to 4 days...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50210332(CHEMBL3889475)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50210334(CHEMBL3948977)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/epsilon(MOUSE)
Hainan University

Curated by ChEMBL
LigandPNGBDBM50238584(CHEMBL4089797)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of dopamine uptake in rat synaptosomal fractionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50210333(CHEMBL3908556)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit alpha/beta/delta/gamma(Homo sapiens (Human))
The Royal Danish School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50210335(CHEMBL3898434)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at alpha1beta1gammadelta nAChR in human TE671/RD cells assessed as reduction in carbamylcholine induced 86Rb+ efflux preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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